Un estudio dado a conocer en Cell Metabolism ha identificado el mecanismo cerebral mediante el cual una proteína llamada SIRT1 retrasa el envejecimiento y aumenta la longevidad. Ambos efectos se asocian también con una dieta baja en calorías, según exponen los autores, de la Escuela de Medicina de la Universidad de Washington (EE UU).
En concreto, el trabajo revela que la sirtuina SIRT1 en ratones promueve la actividad neuronal en zonas muy específicas del hipotálamo del cerebro que desencadenan cambios físicos radicales en el músculo esquelético y aumentan el vigor, la energía y la longevidad. La consecuencia es que, si se le somete a una modificación genética que le hace producir en exceso la proteína SIRT1, un ratón de 12 meses de edad (el equivalente a 70 años en humanos) se muestra tan activo como correspondería a un roedor de tan solo 5 meses. Los ratones con dosis extra de SIRT1 también mostraron un aumento de la temperatura corporal, del consumo de oxígeno y de la actividad física nocturna en comparación con individuos de su misma edad.
Asimismo, se observó un retraso en la muerte por cáncer en los ratones con exceso de SIRT1 frente a los roedores control. Imai ha explicado que el perfil de la longevidad y la salud en estos animales parece ser el resultado de un retraso en el momento en que comienza el declive relacionado con la edad, y no un cambio en el ritmo de envejecimiento.
Si se confirma que el efecto es el mismo en humanos, esta terapia génica podría añadir 13 o 14 años de vida en mujeres y 7 años en hombres.
I visited various web pages however the audio feature for audio
songs existing at this web site is genuinely wonderful.
At this time it sounds like Expression Engine is the preferred blogging platform available right now. (from what I’ve read) Is that what you’re using on your blog?|Outstanding post however I was wanting to know if you could write a litte more on this subject? I’d be very thankful if you could elaborate a little bit more. Thanks!|Hey! I know this is somewhat off topic but I was wondering if you knew where I could get a captcha plugin for my comment form? I’m using the same blog platform as yours and I’m having trouble finding one? Thanks a lot!|When I originally commented I clicked the «Notify me when new comments are added» checkbox and now each time a comment is added I get several e-mails with the same comment. Is there any way you can remove me from that service? Appreciate it!|Hello! This is my first visit to your blog! We are a collection of volunteers and starting a new project in a community in the same niche. Your blog provided us valuable information to work on. You have done a marvellous job!|Hey there! I know this is kind of off topic but I was wondering which blog platform are you using for this site? I’m getting tired of WordPress because I’ve had problems with hackers and I’m looking at options for another platform. I would be great if you could point me in the direction of a good platform.|Hi there! This post couldn’t be written any better! Reading through this post reminds me of my previous room mate! He always kept talking about this. I will forward this article to him. Pretty sure he will have a good read. Thanks for sharing!|Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You obviously know what youre talking about, why waste your intelligence on just posting videos to your blog when you could be giving us something enlightening to read?|Today, I went to the beach front with my children. I found a sea shell and gave it to my 4 year old daughter and said «You can hear the ocean if you put this to your ear.» She placed the shell to her ear and screamed. There was a hermit crab inside and it pinched her ear. She never wants to go back! LoL I know this is completely off topic but I had to tell someone!|The other day, while I was at work, my cousin stole my iphone and tested to see if it can survive a 40 foot drop, just so she can be a youtube sensation. My iPad is now destroyed and she has 83 views. I know this is completely off topic but I had to share it with someone!|I was wondering if you ever thought of changing the page layout of your site? Its very well written; I love what youve got to say. But maybe you could a little more in the way of content so people could connect with it better. Youve got an awful lot of text for only having 1 or 2 images. Maybe you could space it out better?|Hello, i read your blog from time to time and i own a similar one and i was just wondering if you get a lot of spam comments? If so how do you stop it, any plugin or anything you can suggest? I get so much lately it’s driving me mad so any assistance is very much appreciated.|This design is incredible! You definitely know how to keep a reader amused. Between your wit and your videos, I was almost moved to start my own blog (well, almost…HaHa!) Wonderful job. I really loved what you had to say, and more than that, how you presented it. Too cool!|I’m really enjoying the design and layout of your site. It’s a very easy on the eyes which makes it much more pleasant for me to come here and visit more often. Did you hire out a designer to create your theme? Excellent work!|Howdy! I could have sworn I’ve been to this site before but after reading through some of the post I realized it’s new to me. Anyways, I’m definitely glad I found it and I’ll be bookmarking and checking back often!|Good day! Would you mind if I share your blog with my twitter group? There’s a lot of folks that I think would really enjoy your content. Please let me know. Many thanks|Hi, I think your blog might be having browser compatibility issues. When I look at your website in Safari, it looks fine but when opening in Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up! Other then that, great blog!|Wonderful blog! I found it while browsing on Yahoo News. Do you have any suggestions on how to get listed in Yahoo News? I’ve been trying for a while but I never seem to get there! Many thanks|Hello there! This is kind of off topic but I need some advice from an established blog. Is it difficult to set up your own blog? I’m not very techincal but I can figure things out pretty fast. I’m thinking about creating my own but I’m not sure where to start. Do you have any tips or suggestions? With thanks|Hi! Quick question that’s totally off topic. Do you know how to make your site mobile friendly? My web site looks weird when viewing from my iphone 4. I’m trying to find a theme or plugin that might be able to fix this issue. If you have any suggestions, please share. With thanks!|I’m not that much of a online reader to be honest but your blogs really nice, keep it up! I’ll go ahead and bookmark your site to come back later. Many thanks|I love your blog.. very nice colors & theme. Did you design this website yourself or did you hire someone to do it for you? Plz reply as I’m looking to create my own blog and would like to know where u got this from. kudos|Amazing! This blog looks exactly like my old one! It’s on a entirely different topic but it has pretty much the same page layout and design. Excellent choice of colors!|Hey there just wanted to give you a brief heads up and let you know a few of the images aren’t loading correctly. I’m not sure why but I think its a linking issue. I’ve tried it in two different web browsers and both show the same results.|Heya are using WordPress for your blog platform? I’m new to the blog world but I’m trying to get started and set up my own. Do you need any html coding expertise to make your own blog? Any help would be really appreciated!|Hi this is kinda of off topic but I was wanting to know if blogs use WYSIWYG editors or if you have to manually code with HTML. I’m starting a blog soon but have no coding expertise so I wanted to get guidance from someone with experience. Any help would be enormously appreciated!|Hey! I just wanted to ask if you ever have any trouble with hackers? My last blog (wordpress) was hacked and I ended up losing months of hard work due to no back up. Do you have any methods to protect against hackers?|Howdy! Do you use Twitter? I’d like to follow you if that would be okay. I’m undoubtedly enjoying your blog and look forward to new posts.|Hello! Do you know if they make any plugins to safeguard against hackers? I’m kinda paranoid about losing everything I’ve worked hard on. Any suggestions?|Hello there! Do you know if they make any plugins to help with Search Engine Optimization? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good gains. If you know of any please share. Kudos!|I know this if off topic but I’m looking into starting my own weblog and was curious what all is required to get set up? I’m assuming having a blog like yours would cost a pretty penny? I’m not very web savvy so I’m not 100% sure. Any suggestions or advice would be greatly appreciated. Appreciate it|Hmm is anyone else encountering problems with the images on this blog loading? I’m trying to find out if its a problem on my end or if it’s the blog. Any responses would be greatly appreciated.|I’m not sure exactly why but this site is loading incredibly slow for me. Is anyone else having this issue or is it a problem on my end? I’ll check back later on and see if the problem still exists.|Hey there! I’m at work surfing around your blog from my new iphone! Just wanted to say I love reading your blog and look forward to all your posts! Keep up the fantastic work!|Wow that was unusual. I just wrote an extremely long comment but after I clicked submit my comment didn’t show up. Grrrr… well I’m not writing all that over again. Anyway, just wanted to say wonderful blog!|Hi exceptional website! Does running a blog similar to this require a massive amount work? I’ve very little knowledge of coding however I was hoping to start my own blog soon. Anyhow, if you have any recommendations or techniques for new blog owners please share. I understand this is off subject nevertheless I simply wanted to ask. Appreciate it!|Hey there! I know this is somewhat off-topic however I needed to ask. Does running a well-established blog like yours take a massive amount work? I’m completely new to operating a blog but I do write in my diary every day. I’d like to start a blog so I can easily share my experience and thoughts online. Please let me know if you have any recommendations or tips for brand new aspiring blog owners. Thankyou!|Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this. Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.|I don’t know whether it’s just me or if perhaps everybody else encountering problems with your site. It appears like some of the text in your content are running off the screen. Can someone else please provide feedback and let me know if this is happening to them too? This might be a issue with my web browser because I’ve had this happen before. Kudos|First off I want to say fantastic blog! I had a quick question in which I’d like to ask if you do not mind. I was interested to know how you center yourself and clear your mind before writing. I have had a difficult time clearing my mind in getting my thoughts out there. I truly do enjoy writing but it just seems like the first 10 to 15 minutes are usually wasted just trying to figure out how to begin. Any recommendations or hints? Many thanks!
It’s what im looking for! Thank you!
«wow, awesome blog.Thanks Again. Really Great.»